Louis Pasture and the 1st Rabies Vaccine
By Noah Kuschel and Cora Dresser
Why we choose this topic:
We decided to do 1st rabies vaccine the 1st day it was announced. We discussed it walking to lunch. Cora suggested it and Noah was up for any project. We walked up to the teacher the next day and told her our idea.
Our project was as deep as it will get into subject. We were ready to research.
How we conducted our research:
We started by looking for pictures and websites. We then made a website to put the pictures and research we had done 1st. we found our resources all over the Internet.
We didn’t go to the library. We learned so much on the websites in the Internet. It was easy to research and we were on a roll. We spent allot of time printing and highlighting our research.
How we developed our website:
We selected our presentation by thinking which presentation will be less frequently used. We used a computer and a highlighter. The most frustrating part of our project was typing in everything we researched for quite a time.
How our topic relates to the theme:
It was fit for the topic of the year. It fit for these reasons; Revolution is fit for the way it revolutionized vaccinations to come. Reform is fit for our project because it brought less death from the plague on society known as rabies. Reaction was people didn’t need to worry as much about rabies anymore.
Annotated Bibliography
We looked up many things about rabies and wrote down the websites we went to. We wrote and highlighted lots of stuff about our subject. We looked up both primary and secondary resources and wrote everything down in our own words and added a few quotes. Many websites are on the Internet about rabies, and we use a fraction of them. We learned so much about rabies, we never even thought we would learn that much about rabies in our whole live’s. So much research went into this project it took a couple of months to finish.
We decided to do 1st rabies vaccine the 1st day it was announced. We discussed it walking to lunch. Cora suggested it and Noah was up for any project. We walked up to the teacher the next day and told her our idea.
Our project was as deep as it will get into subject. We were ready to research.
How we conducted our research:
We started by looking for pictures and websites. We then made a website to put the pictures and research we had done 1st. we found our resources all over the Internet.
We didn’t go to the library. We learned so much on the websites in the Internet. It was easy to research and we were on a roll. We spent allot of time printing and highlighting our research.
How we developed our website:
We selected our presentation by thinking which presentation will be less frequently used. We used a computer and a highlighter. The most frustrating part of our project was typing in everything we researched for quite a time.
How our topic relates to the theme:
It was fit for the topic of the year. It fit for these reasons; Revolution is fit for the way it revolutionized vaccinations to come. Reform is fit for our project because it brought less death from the plague on society known as rabies. Reaction was people didn’t need to worry as much about rabies anymore.
Annotated Bibliography
We looked up many things about rabies and wrote down the websites we went to. We wrote and highlighted lots of stuff about our subject. We looked up both primary and secondary resources and wrote everything down in our own words and added a few quotes. Many websites are on the Internet about rabies, and we use a fraction of them. We learned so much about rabies, we never even thought we would learn that much about rabies in our whole live’s. So much research went into this project it took a couple of months to finish.
"Over 100 years ago, in 1885, Louis Pasteur developed a crude nerve tissue vaccine for the postexposure treatment of rabies. This form of vaccination used dessicated infected tissue and was found to prevent rabies infection in a 9 year old boy named Joseph Meister. Following Pasteur's initial vaccine, inactivated vaccines were developed. This inactivated form of vaccine was produced by serial dilutions followed by sterilization with chemical agents that inactivated the virus. Further improvements to the inactivated virus vaccine developed through growing virus in various animal tissues and inactivation by UV light or phenol. Semple (derived from sheep or goat brain) vaccines examples of inactivated virus and are still used throughout the world today. They are poorly efficacious and poorly tolerated. Side-effects include
the demyelination of central or peripheral nervous system in 1 out of 3000, and is occasionally fatal.
http://www.brown.edu/Courses/Bio_160/Projects1999/rabies/vacc.html